September 2, 2016
Discovery of New Chemical Entities for Alzheimer's Disease Tauopathy
The project is supported by a Phase I SBIR grant award from the National Institute on Aging (1R43AG053137-01A1). Experimental work will be subcontracted to the laboratory of Dr. Kuret at Ohio State University.
Alzheimer’s disease is the most prevalent dementing illness of the elderly. It is defined in part by the appearance of cellular lesions composed of aggregates of the microtubule-associated protein tau. This project seeks to identify novel tau aggregation inhibitors as potentially disease modifying therapeutics for AD.