September 1, 2016 Quantum Model Repurposing of Cetromycin for Liver Stage Malaria Project Narrative: Cethromycin was identified by a published quantum model computational analysis for liver- stage malaria drugs. This cethromycin preclinical mouse malaria liver-stage work will build a more solid evidence base for a phase 2, controlled human malaria infection clinical trial. The long-term outcome will be a new safe, effective malaria prophylaxis drug and/or a replacement of primaquine for the dormant liver-stage of P. vivax/ovale. Link to the FOA Link to NIH RePORT |